L-Alanyl-L-Glutamine

A synthetic glutamine dipeptide

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库存: 现货

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10g

￥712.00

570.00

- +
25g

￥1437.00

1150.00

- +
50g

￥2525.00

2020.00

- +
100g

￥4287.00

3430.00

- +

已选 0 种 0 瓶

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货号: ajci72300
CAS: 39537-23-0
别名: L-丙氨酸-L-谷氨酰胺
分子式: C8H15N3O4
分子量: 217.2
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 2 mg/ml
储存: Store at RT
库存: 现货

Background

L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.