MeOSuc-AAPV-pNA

A substrate for neutrophil elastase and proteinase 3

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥500.00

400.00

- +
10mg

￥900.00

720.00

- +
25mg

￥1762.00

1410.00

- +
50mg

￥2012.00

1610.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci72554
CAS: 70967-90-7
别名: N-甲氧基琥珀酰-丙酰氨-丙酰氨-脯酰氨-缬氨酸对硝基酰苯胺
分子式: C27H38N6O9
分子量: 590.6
纯度: >98%
溶解度: DMF: 2 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 25 mg/ml
储存: Store at -20°C
库存: 现货

Background

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.