Nafarelin (acetate)

A GNRH agonist

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库存: 现货

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数量
500ug

￥937.00

750.00

- +
1mg

￥1775.00

1420.00

- +
5mg

￥6937.00

5550.00

- +
10mg

￥11887.00

9510.00

- +

已选 0 种 0 瓶

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货号: ajci72862
CAS: 76932-60-0
别名:
分子式: C66H83N17O13?XC2H4O2
分子量: 1322.5
纯度: >98%
溶解度: DMSO: Slightly Soluble,Methanol: Slightly Soluble,Water: Slightly Soluble
储存: Store at -20°C
库存: 现货

Background

Nafarelin is an agonist of gonadotropin-releasing hormone (GNRH). It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones. In vivo, nafarelin (0.5-2.0 μg/kg, s.c.) reduces plasma levels of luteinizing hormone and testosterone as well as testicular volume, sperm count, sperm motility, and duration of ejaculation in male dogs. Nafarelin (32 μg/animal per day) inhibits estrus in female beagle dogs. It also reduces the volume of endometrial tissue in a rat model of endometriosis. Formulations containing nafarelin have been used in the treatment of endometriosis and central precocious puberty.