p-Nitrobenzyl mesylate

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

可选规格

包装

价格

促销价

数量
500ug

￥661.00

528.00

- +
1mg

￥1111.00

888.00

- +
5mg

￥4167.00

3333.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

p-Nitrobenzyl mesylate (PNBM) is a reagent that is used to alkylate thiophosphates, forming thiophosphate ester epitopes that can be recognized by specific antibodies.

货号：ajci73568
CAS：39628-94-9
分子式：C8H9NO5S
分子量：231.2
纯度：98%
存储：Store at -20°C
库存：现货

Background:

p-Nitrobenzyl mesylate (PNBM) is a reagent that is used to alkylate thiophosphates, forming thiophosphate ester epitopes that can be recognized by specific antibodies.¹ Substrates phosphorylated with adenosine 5'-(γ-thio)-triphosphate or N⁶-benzyl-ATPγS can be alkylated by PNBM. ^2,3The tagged substrates can be isolated by immunoprecipitation or immunoaffinity purification, or they can be detected by immunoblotting.

参考文献:

1. Allen, J.J., Li, M., Brinkworth, C.S., et al. A semisynthetic epitope for kinase substrates. Nat. Methods 4(6), 511-516 (2007).

2. Kumar, V., Weng, Y.-C., Geldenhuys, W.J., et al. Generation and characterization of ATP analog-specific protein kinase Cδ. J. Biol. Chem. 290(4), 1936-1951 (2015).

3. Leissing, F., Nomoto, M., Bocola, M., et al. Substrate thiophosphorylation by Arabidopsis mitogen-activated protein kinases. BMC Plant Biol. 16(48), (2016).