Prostaglandin A2 methyl ester

Lipophilic analog of PGA2

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
1mg

￥1125.00

900.00

- +
5mg

￥4987.00

3990.00

- +
10mg

￥8875.00

7100.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci73650
CAS: 31753-19-2
别名: Medullin methyl ester, PGA2 methyl ester
分子式: C21H32O4
分子量: 348.5
纯度: >98%
溶解度: DMF: 75 mg/ml,DMSO: 50 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 2 mg/ml
储存: Store at -20°C
库存: 现货

Background

Prostaglandin A2 (PGA2) is a naturally occurring PG in gorgonian corals where it may function in self defense. At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at G1 and G2/M by preventing activation of cyclin-dependent kinases. At similar concentrations, it stabilizes transcripts for the tumor suppressor SMAR1, downregulating cyclin D1 expression. PGA2 also induces apoptosis in HL-60 cells. Prostaglandin A2 methyl ester is a lipophilic analog of PGA2 which may be more amenable for certain formulations or applications. Its biological properties have not been evaluated.