安捷凯生物医药
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  • Syk Inhibitor
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Syk Inhibitor

Potently blocks spleen tyrosine kinase activity

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

Syk Inhibitor的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥512.00
    410.00
    - +
  • 1mg
    ￥937.00
    750.00
    - +
  • 5mg
    ￥2062.00
    1650.00
    - +
  • 10mg
    ￥3625.00
    2900.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci74196
  • CAS: 622387-85-3
  • 别名: OXSI 2, Spleen Tyrosine Kinase
  • 分子式: C18H15N3O3S
  • 分子量: 353.4
  • 纯度: >98%
  • 溶解度: DMSO: 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs (ITAMs) of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibitor is an oxindole compound that potently blocks Syk activity with an IC50 value of 5 nM and inhibits FcεRI-mediated rat RBL-2H3 basophil cell degranulation (EC50 = 1.4 μM). At 2 μM, this compound completely abolishes convulxin-induced platelet aggregation and shape change.

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