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  • Voacamine
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Voacamine

An alkaloid with diverse biological activities

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Voacamine的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥600.00
    480.00
    - +
  • 1mg
    ￥1150.00
    920.00
    - +
  • 5mg
    ￥2712.00
    2170.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci74542
  • CAS: 3371-85-5
  • 别名: 老刺木胺
  • 分子式: C43H52N4O5
  • 分子量: 704.9
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Voacamine is an alkaloid originally isolated from Voacanga that has diverse biological activities. It is a cannabinoid receptor 1 (CB1) antagonist (IC50 = 41 nM). Voacamine (1-10 µg/ml) time- and dose-dependently decreases survival of U2OS and multi-drug resistant U2OS (U2OS/DX) osteosarcoma cells and induces autophagy but not apoptosis. It also has antimalarial activity, inhibiting growth of P. falciparum in vitro at the trophozoite and schizont stages and reducing parasitemia in mice infected with P. yoelii when administered at doses of 2.5, 5, and 10 mg/kg.

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