An essential ω-6 PUFA
Linoleic acid is an essential ω-6 polyunsaturated fatty acid (PUFA).1 It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 μM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay.2 Rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin.3 Linoleic acid (peroxide free) contains the antioxidant BHT . BHT-free linoleic acid is also available.
亚油酸是一种必需的ω-6多不饱和脂肪酸（PUFA）。它是各种食物中最丰富的PUFA，膳食摄入亚油酸的来源包括植物油、肉类、坚果、种子和鸡蛋。亚油酸（30 μM）增加了IEC-6大鼠肠上皮细胞在创面愈合实验中的迁移。饮食中缺乏亚油酸的大鼠体重下降，并且肝脏和血清磷脂中的二十碳三烯酸/花生四烯酸比值增加，前掌皮肤有轻微的脱屑。亚油酸（去过氧化物）含有抗氧化剂BHT。也有不含BHT的亚油酸产品。
1.Whelan, J., and Fritsche, K.Linoleic acidAdv. Nutr.4(3)311-312(2013) 2.Ruthig, D.J., and Meckling-Gill, K.A.Both (n-3) and (n-6) fatty acids stimulate wound healing in the rat intestinal epithelial cell line, IEC-6J. Nutr.129(10)1791-1798(1999) 3.Cunnane, S.C., and Anderson, M.J.Pure linoleate deficiency in the rat: Influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidationJ. Lipid Res.38(4)805-812(1997)
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