Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin)

Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin) 通过与阿片受体结合来调节人体免疫功能并抑制肿瘤生长。

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库存: 现货

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25mg

￥1025.00

820.00

- +
50mg

￥1712.00

1370.00

- +
100mg

￥2812.00

2250.00

- +

已选 0 种 0 瓶

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货号: ajce45874
CAS: 58569-55-4
别名: 蛋氨酸脑啡肽; Met-Enkephalin; Methionine enkephalin
分子式: C27H35N5O7S
分子量: 573.66
纯度: >98%
溶解度: DMSO : ≥ 40 mg/mL (69.73 mM);Water : 6.67 mg/mL (11.63 mM)
储存: Store at -20°C
库存: 现货

Background

Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems. MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells. MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells. All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy. Furthermore, they reveal a relationship between the endocrine and immune systems[1].

[1]. Zhao D, et al. Methionine enkephalin, its role in immunoregulation and cancer therapy. Int Immunopharmacol. 2016 Feb 23. pii: S1567-5769(16)30050-9.