ACTH 1-13 (Adrenocorticotropic Hormone (1-13)) 是一种 13-aa 肽，在乙醇诱导的大鼠胃损伤模型中具有细胞保护作用。
ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease[2].
ACTH (1-13) alone or in combination with met-enkephalin shows potent cytoprotective effects in the model of ethanol induced gastric lesions in rats, and has immunomodulatory effects[1].
[1]. Mulabegovi? N, et al. Pharmacodynamic properties of a combination of met-enkephalin and alpha 1-13 adrenocorticotropic hormone. Med Arh. 2008;62(1):41-4. [2]. Allen MJ, et al. Adrenocorticotropic Hormone (ACTH). StatPearls. 2018.7.
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