Carbendazim

A degradation product and active ingredient of benomyl

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库存: 现货

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数量
100mg

￥537.00

430.00

- +
500mg

￥750.00

600.00

- +
1g

￥975.00

780.00

- +
5g

￥2912.00

2330.00

- +

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金额: ￥0.00

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Background

Carbendazim is the degradation product and active ingredient of the carbamate fungicide benomyl.^1,2 Carbendazim (100 ?M) disrupts the growth of S. cerevisiae by inhibiting microtubule polymerization.¹ It impairs meiosis and steroidogenesis in an ex vivo rat model of seminiferous tubules and increases prostate weight in rats when administered at a dose of 100 mg/kg but does not affect other testosterone-dependent or estrogen-dependent tissues.^3,4

1.Quinlan, R.A., Pogson, C.I., and Gull, K.The influence of the microtubule inhibitor, methyl benzimidazol-2-yl-carbamate (MBC) on nuclear division and the cell cycle in Saccharomyces cerevisiaeJ. Cell. Sci.46341-352(1980) 2.Chiba, M., and Veres, D.F.Fate of benomyl and its degradation compound methyl 2-benzimidazolecarbamate on apple foliageJ. Agric. Food Chem.29(3)588-590(1981) 3.Pisani, C., Voisin, S., Arafah, K., et al.Ex vivo assessment of testicular toxicity induced by carbendazim and iprodione, alone or in a mixtureALTEX33(4)393-413(2016) 4.Rama, E.M., Bortolan, S., Vieira, M.L., et al.Reproductive and possible hormonal effects of carbendazimRegul. Toxicol. Pharmacol.69(3)476-486(2014)