Benzcyclane (Bencyclane)

苯环烷(Bencyclane) (Bencyclane; Benzcyclan) 是一种血小板聚集抑制剂和血管扩张剂，对多种外周循环障碍有效。

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库存: 现货

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1mg

￥2150.00

1720.00

- +
5mg

￥4275.00

3420.00

- +
10mg

￥7262.00

5810.00

- +
20mg

￥12712.00

10170.00

- +

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Background

Benzcyclane (Bencyclane; Benzcyclan) is a platelet aggregation inhibitor and a vasodilator effective in a variety of peripheral circulation disorders.

Benzcyclane, although capable of aggregating platelets by itself at very high concentrations, shows a striking inhibitory effect, over a wide range of concentrations, both on platelet aggregation induced by ADP, epinephrine or collagen and on platelet adhesiveness to glass or collagen. Clot retraction is also clearly inhibited[1]. Benzcyclane induces use-dependent inhibition of Na channels in muscle, similarly as do class 1 antiarrhytnmic drugs. Inhibition was observed with both normal and cevadine-modified Na channels[2].

[1]. Ponari O, et al. In vitro effects of bencyclan on coagulation, fibrinolysis and platelet function. Arzneimittelforschung. 1976;26(8):1532-8. [2]. Nánási PP, et al. Effects of bencyclane on normal and cevadine-modified Na channels in frog skeletal muscle. Gen Physiol Biophys. 1989 Oct;8(5):447-58.