Temoporfin (m-THPC)

A light-activated chlorin

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库存: 现货

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包装

价格

促销价

数量
2mg

￥1562.00

1250.00

- +
5mg

￥2375.00

1900.00

- +
10mg

￥4062.00

3250.00

- +
25mg

￥7587.00

6070.00

- +
50mg

￥11762.00

9410.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells.^1,2 When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor.^1,2 Different approaches to using photodynamic therapy with temoporfin in palliative care are currently of interest.^3,4

1.Alian, W., Andersson-Engels, S., Svanberg, K., et al.Laser-induced fluorescence studies of meso-tetra(hydroxyphenyl)chlorin in malignant and normal tissues in ratsBr. J. Cancer70(5)880-885(1994) 2.Ris, H.B., Altermatt, H.J., Inderbitzi, R., et al.Photodynamic therapy with chlorins for diffuse malignant mesothelioma: Initial clinical resultsBr. J. Cancer64(6)1116-1120(1991) 3.Reshetov, V., Lassalle, H.P., Fran?ois, A., et al.Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): Comparison of treatment efficacy and distribution characteristics in vivoInt. J. Nanomedicine83817-3831(2013) 4.Succo, G., Rosso, S., Fadda, G.L., et al.Salvage photodynamic therapy for recurrent nasopharyngeal carcinomaPhotodiagnosis Photodyn.Ther.11(2)63-70(2014)