N-Bis(2-hydroxypropyl)nitrosamine (DHPN)

N-双(2-羟丙基)亚硝胺 (DHPN) 是一种具有致癌活性的物质。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
10mg

￥637.00

510.00

- +
25mg

￥1287.00

1030.00

- +
50mg

￥2037.00

1630.00

- +
100mg

￥3125.00

2500.00

- +
200mg

￥5237.00

4190.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajce50406
CAS: 53609-64-6
别名: N-亚硝基二异丙醇胺,DHPN; Di(2-hydroxypropyl)nitrosamine; Diisopropanolnitrosamine
分子式: C6H14N2O3
分子量: 162.19
纯度: >98%
溶解度: DMSO : ≥ 125 mg/mL (770.70 mM)
储存: Store at -20°C
库存: 现货

Background

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.

N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity[1].

N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses[1]. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats[2].

[1]. Konishi Y, et al. Effect of dose on the carcinogenic activity of orally administered N-bis(2-hydroxypropyl)nitrosamine in rats. Gan. 1978 Aug;69(4):573-7. [2]. Zhang J, et al. Low dose of Bisphenol A enhance the susceptibility of thyroid carcinoma stimulated by DHPN and iodine excess in F344 rats. Oncotarget. 2017 Jul 22;8(41):69874-69887.