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  • LM985
LM985的可视化放大

LM985

LM985是一种带有黄酮环结构的化合物,具有抗肿瘤功效。

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LM985的二维码
  • 库存: 现货
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  • 1mg
    ¥16950.00
    13560.00
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  • 5mg
    ¥42387.00
    33910.00
    - +
  • 10mg
    ¥72062.00
    57650.00
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  • 货号: ajce51060
  • CAS: 87626-56-0
  • 别名:
  • 分子式: C23H25NO4
  • 分子量: 379.45
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.


LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1].


LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2].


[1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600.

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