Isoastragaloside I (Isoastragaloside-I)

异黄芪苷 I (Isoastragaloside-I) 是一种来自药材黄芪的天然化合物；具有提高脂联素生成的活性。

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库存: 现货

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5mg

￥2150.00

1720.00

- +
10mg

￥4062.00

3250.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Isoastragaloside I is a natural compound from the medicinal herb Radix Astragali; possesses the activity of elevating adiponectin production.IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines. Furthermore, an additive effect on induction of adiponectin production was observed between these two compounds and rosiglitazone, a thiazolidinedione class of insulin-sensitizing drugs. Chronic administration of astragaloside II and isoastragaloside I in both dietary and genetic obese mice significantly elevated serum levels of total adiponectin and selectively increased the composition of its high molecular weight oligomeric complex.

[1]. Xu A, et al. Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice. Endocrinology. 2009 Feb;150(2):625-33.