Lenampicillin hydrochloride (KBT 1585 hydrochloride)

Lenampicillin hydrochloride (KBT 1585 hydrochloride) (KBT 1585 hydrochloride) 是 Ampicillin 的口服活性前药，是一种有效的 β-内酰胺抗菌剂，可抑制细菌青霉素结合蛋白（转肽酶）。 Lenampicillin hydrochloride (KBT 1585 hydrochloride) 与 Ampicillin 相比具有改善的吸收和减少的副作用，用于化脓性皮肤和软组织感染的调查。

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库存: 现货

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数量
2mg

￥950.00

760.00

- +
5mg

￥1662.00

1330.00

- +
10mg

￥2700.00

2160.00

- +

已选 0 种 0 瓶

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货号: ajce52536
CAS: 80734-02-7
别名: 盐酸仑氨苄西林; KBT 1585 hydrochloride
分子式: C21H24ClN3O7S
分子量: 497.95
纯度: >98%
溶解度: Soluble in DMSO
储存: Store at -20°C, sealed storage, away from moisture and light
库存: 现货

Background

Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93. [2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.