现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • 7-xylosyltaxol
7-xylosyltaxol的可视化放大

7-xylosyltaxol

A taxane with microtubule disruptor and anticancer activities

原价
¥6687-10575
价格
5350-8460
7-xylosyltaxol的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajce54636
  • CAS: 90332-66-4
  • 别名: 7-木糖基紫杉醇,7-Xylosylpaclitaxel; Taxol-7-xyloside
  • 分子式: C52H59NO18
  • 分子量: 986.02
  • 纯度: >98%
  • 溶解度: DMSO: 10 mM
  • 储存: Store at -20°C
  • 库存: 现货

Background

7-Xylosyltaxol is a taxane and derivative of paclitaxel that has been found in T. chinensis and has microtubule disruptor and anticancer activities.1,2,3 It induces the disassembly of pig brain and Physarum microtubules in cell-free assays (IC50s = 0.2 and 0.4 ?M, respectively).2 7-Xylosyltaxol inhibits proliferation of A549, MCF-7, A2780, HCT-8, and SW480 cancer cells with IC50 values of 0.39, 0.16, 0.85, 5.9, and 5.6 ?M, respectively.3


1.Yu, S.-S., Sun, Q.-W., Zhang, X.-P., et al.Content and distribution of active components in cultivated and wild Taxus chinensis var. mairei plantsYing Yong Sheng Tai Xue Bao23(10)2641-2647(2012) 2.Lataste, H., Senilh, V., Wright, M., et al.Relationships between the structures of taxol and baccatine III derivatives and their in vitro action on the disassembly of mammalian brain and Physarum amoebal microtubulesProc. Natl. Acad. Sci. USA81(13)4090-4094(1984) 3.Sun, Z.-H., Chen, Y., Guo, Y.-Q., et al.Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. maireiBioorg. Med. Chem. Lett.25(6)1240-1243(2015)

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服