Aceglutamide

An acetylated form of L-glutamine

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500mg

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货号: ajce54698
CAS: 2490-97-3
别名: 乙酰谷酰胺; α-N-Acetyl-L-glutamine; N2-Acetylglutamine
分子式: C7H12N2O4
分子量: 188.18
纯度: >98%
溶解度: Water: 33.33 mg/mL (177.12 mM); DMSO: 16.67 mg/mL (88.59 mM)
储存: Store at -20°C
库存: 现货

Background

N-acetyl-L-Glutamine is an acetylated form of the conditionally essential amino acid L-glutamine . It decreases infarct volume and prevents neuronal apoptosis in the substantia nigra in a rat model of cerebral ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).¹ N-acetyl-L-Glutamine (8.28 g/animal per day) prevents decreases in body weight in protein-energy malnourished pigs.² Formulations containing N-acetyl-L-glutamine have been used as dietary supplements.

1.Zhang, R., Yang, N., Ji, C., et al.Neuroprotective effects of Aceglutamide on motor function in a rat model of cerebral ischemia and reperfusionRestor. Neurol. Neurosci.33(5)741-759(2015) 2.López-Pedrosa, J.M., Manzano, M., Baxter, J.H., et al.N-acetyl-L-glutamine, a liquid-stable source of glutamine, partially prevents changes in body weight and on intestinal immunity induced by protein energy malnutrition in pigsDig. Dis. Sci.52(3)650-658(2007)