Acetyllovastatin 是一种 Lovastatin 的乙酸盐,对乙酰胆碱酯酶有中度抑制作用,IC50 为 79 μg/mL。Lovastatin 具有抗真菌活性,并抑制许多转化细胞系的增殖。
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Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines[1]. IC50: 79 μg/mL (The enzyme acetylcholinesterase)[1]
[1]. Cazar, et al. Antimicrobial Butyrolactone I Derivatives from the Ecuadorian Soil Fungus Aspergillus terreus Thorn. var terreus. World Journal of Microbiology and Biotechnology, 2005,21(6-7), 1067-1075.
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