Epirubicin

An anthracycline antitumor antibiotic

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥1412.00

1130.00

- +
10mg

￥2175.00

1740.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

Epirubicin is a stereoisomer of the antitumor anthracycline doxorubicin that undergoes β-glucuronidation, which partially detoxifies the dose-limiting side effects that are present with doxorubicin.¹ Compared to doxorubicin, epirubicin is equally cytotoxic to HeLa cells (ID₅₀s = 9 μM).¹ When used either alone or in combination therapies, epirubicin has been shown to demonstrate high rates of complete or partial remission in various cancers including advanced ovary, lymphomas, breast, pancreas, gastric, hepatocellular carcinoma, head and neck tumors, and colorectal.^1,2

1.Arcamone, F.Properties of antitumor anthracyclines and new developments in their application: Cain memorial award lectureCancer Res.45(12 Pt 1)5995-5999(1985) 2.Yao, X., Hosenpud, J., Chitambar, C.R., et al.A phase II study of concurrent docetaxel, epirubicin and cyclophospha-mide as a neoadjuvant chemotherapy regimen in patients with locally advanced breast cancerJ. Cancer3145-151(2012)