现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • Lofexidine
Lofexidine的可视化放大

Lofexidine

An α2-adrenergic receptor agonist

价格
0-880
Lofexidine的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajce57196
  • CAS: 31036-80-3
  • 别名: 洛非西定
  • 分子式: C11H12Cl2N2O
  • 分子量: 259.13
  • 纯度: >98%
  • 溶解度: DMSO: 62.5 mg/mL (241.19 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Lofexidine is an α2-adrenergic receptor agonist (Kd = 7.6 nM for rat cerebral cortex membranes) that has transient antihypertensive effects.1,2 It is used in managing opioid withdrawal symptoms during detoxification from heroin and methadone.3,4


1.Jarrott, B., Louis, W.J., and Summers, R.J.Characterization of central α-adrenoceptors using 3H-clonidine and its derivativesChest83(2 Suppl)339-340(1983) 2.Bennett, D.A., and Lal, H.Discriminative stimuli produced by clonidine: An investigation of the possible relationship to adrenoceptor stimulation and hypotensionJ. Pharmacol. Exp. Ther.223(3)642-648(1982) 3.Ling, W., Mooney, L., Zhao, M., et al.Selective review and commentary on emerging pharmacotherapies for opioid addictionSubst. Abuse Rehabil.2181-188(2011) 4.Gerra, G., Zaimovic, A., Giusti, F., et al.Lofexidine versus clonidine in rapid opiate detoxificationJ. Subst. Abuse Treat.21(1)11-17(2001)

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服