Odiparcil

Odiparcil (SB-424323) 是一种具有口服活性 beta-d-thioxyloside 类似物，具有抗血栓形成活性，可降低不良出血事件的风险，Odiparcil (SB-424323) 是一种间接凝血酶抑制剂，通过激活抗凝血酶 II (肝素辅助因子 II) 发挥其抗凝血作用。

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库存: 现货

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数量
5mg

￥2725.00

2180.00

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10mg

￥0.00

0.00

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50mg

￥0.00

0.00

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已选 0 种 0 瓶

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Background

Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2]. Thrombin[2]

[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70 [2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.