5,15-Diacetyl-3-benzoyllathyrol

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20mg

￥4507.00

4056.00

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Extracted?from?Euphorbiaceae Euphorbia lathyris dry mature seeds;Store?the?product?in?sealed,?cool?and?dry?condition

货号：ajcn4548
CAS：218916-52-0
分子式：C31H38O7
分子量：522.63
纯度：98%
存储：Store at -20°C
库存：现货

Background:

5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.

5,15-Diacetyl-3-benzoyllathyrol shows anticancer activity in vitro against lung cancer A549 cells and the IC50 values are 34.04±3.99 μM. Furthermore, 5,15-Diacetyl-3-benzoyllathyrol can induce apoptosis in A549 cells via the mitochondrial pathway including loss of mitochondrial potential and release of cytochrome c[1].

参考文献:
[1]. Zhang JY, et al. Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway. Molecules. 2011 Apr 15;16(4):3222-31.