A triterpene saponin with antiviral and antioxidant activities
Hederasaponin B is a triterpene saponin that has been found in H. helix and has antiviral and antioxidant activities.1,2 It inhibits the cytopathic effect induced by the enterovirus 71 (EV71) genotypes C3 and C4a (EC50s = 24.77 and 41.77 ?g/ml, respectively), as well as reduces expression of the viral structural capsid protein VP2, in Vero cells.1 Hederasaponin B (100, 150, and 200 ?g/ml) inhibits superoxide generation in human neutrophils.2
1.Song, J., Yeo, S.-G., Hong, E.-H., et al.Antiviral activity of hederasaponin B from Hedera helix against enterovirus 71 subgenotypes C3 and C4aBiomol. Ther. (Seoul)22(1)41-46(2014) 2.Chen, X., Lu, J., He, W., et al.Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeanaFitoterapia80(2)105-111(2009)
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