Hederasaponin B

A triterpene saponin with antiviral and antioxidant activities

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库存: 现货

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数量
1mg

￥850.00

680.00

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5mg

￥2550.00

2040.00

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10mg

￥4312.00

3450.00

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货号: ajcn5186
CAS: 36284-77-2
别名: 刺五加叶中
分子式: C59H96O25
分子量: 1205.38
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 5 mg/ml
储存: Store at -20°C
库存: 现货

Background

Hederasaponin B is a triterpene saponin that has been found in H. helix and has antiviral and antioxidant activities.^1,2 It inhibits the cytopathic effect induced by the enterovirus 71 (EV71) genotypes C3 and C4a (EC₅₀s = 24.77 and 41.77 ?g/ml, respectively), as well as reduces expression of the viral structural capsid protein VP2, in Vero cells.¹ Hederasaponin B (100, 150, and 200 ?g/ml) inhibits superoxide generation in human neutrophils.²

1.Song, J., Yeo, S.-G., Hong, E.-H., et al.Antiviral activity of hederasaponin B from Hedera helix against enterovirus 71 subgenotypes C3 and C4aBiomol. Ther. (Seoul)22(1)41-46(2014) 2.Chen, X., Lu, J., He, W., et al.Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeanaFitoterapia80(2)105-111(2009)