(+)-Corynoline

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20mg

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2288.00

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Extracted from corydalis sheareri S. Moore;Store the product in sealed,cool and dry condition

货号：ajcn5550
CAS：18797-79-0
分子式：C21H21NO5
分子量：367.14
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Corynoline, isolated from Corydalis incise (Papaveraceae), is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].

参考文献:
[1]. Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9.
[2]. Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41(5):1640-1647.