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  • Anti-Inflammatory Peptide 1
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Anti-Inflammatory Peptide 1

原价
¥709-1367
价格
638-1230
Anti-Inflammatory Peptide 1的二维码

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PLA2 inhibitor

货号:ajcp4490
CAS:118850-71-8
分子式:C45H82N12O14S2
分子量:1079.33
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.


参考文献:
1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.


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