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JWG-071
JWG-071 是首次报道的 ERK5 激酶选择性化学探针。JWG-071 提高了 ERK5 活性和 BRD4 选择性。JWG-071 将是反卷积 ERK5 和 BRD4 药理学急需的化学探针。
Dopamine-d4 (hydrochloride)
An internal standard for the quantification of dopamine
LRRK2-IN-1
A selective LRRK2 inhibitor
PFE-360
PFE-360(PF-06685360) is a brain-penetrant and selective LRRK2 small-molecule kinase inhibitors.
GNE-7915
HG-10-102-01
A brain penetrant inhibitor of wild-type and G2019S mutant LRRK2
CZC-25146 hydrochloride
A potent LRRK2 inhibitor
GNE-7915 tosylate
CZC 54252 hydrochloride
An LRRK2 inhibitor
GSK2578215A
ERK5-IN-1
An ERK5 inhibitor
JH-II-127
An inhibitor of wild-type and mutant forms of LRRK2
GNE0877
PF-06447475
PF-06447475 是一种高效、选择性和脑渗透性 LRRK2 抑制剂,IC50 为 3 nM。
MLi-2