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FLT3-IN-4
FLT3-IN-4 是一种口服有效的 Fms 样酪氨酸受体激酶 3 (FLT3; IC50= 7 nM) 抑制剂,可用于治疗急性髓性白血病。
UNC2541
UNC2541 is a potent and specific inhibitor of Mer tyrosine kinase (MerTK) that binds in the MerTK ATP pocket with IC50 of 4.4 nM. UNC2541 inhibits phosphorylated MerTK (pMerTK) with EC50 of 510 nM.
G-749
An FLT3 kinase inhibitor
Dovitinib Dilactic acid
FLT3 inhibitor
Quizartinib (AC220)
An inhibitor of FLT3
UNC2025 hydrochloride
An orally bioavailable inhibitor of Mer and Flt3
BPR1J-097
An FLT3 inhibitor
TCS 359
A cell-permeable FLT3 inhibitor
Tandutinib (MLN518)
An antagonist of PDGFRβ, FLT3, and c-Kit
Gilteritinib
A FLT3 inhibitor
FLT3 Inhibitor III
A potent, highly selective inhibitor of FLT3
MRX-2843 (UNC2371)
A Mer and FLT3 inhibitor
UNC2025
AZM475271 (M475271)
An inhibitor of c-Src kinase
FLT3-IN-2
An inhibitor of FLT3, c-Kit, and c-FMS