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BGJ398
An FGFR inhibitor
SSR128129E
CH5183284 (Debio-1347)
An inhibitor of FGFR1, 2, and 3
BLU9931
A selective FGFR4 inhibitor
PD 161570
An inhibitor of FGFR1
LY2874455
A pan-FGFR inhibitor
AZD4547
A selective inhibitor of FGFR tyrosine kinases
SU 5402
An inhibitor of VEGFR2, FGFR1, and PDGFRβ
ACTB-1003
A multi-kinase inhibitor
NVP-BGJ398 phosphate
NVP-BGJ398 phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) 是一种有效的 FGFR 家族抑制剂,对 FGFR1、FGFR2、FGFR3 和 FGFR4 的 IC50 分别为 0.9 nM、1.4 nM、1 nM 和 60 nM。
TSU-68 (SU6668,Orantinib)
An inhibitor of select receptor tyrosine kinases
FIIN-2
PD 173074
Inhibitor of tyrosine kinase activity of fibroblast growth factor receptors
BLU-554
A potent inhibitor of FGFR4
Erdafitinib