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  • Ammonium tetrathiomolybdate(VI)
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Ammonium tetrathiomolybdate(VI)

Ammonium tetrathiomolybdate(VI) 是一种铜螯合剂,也是一类硫化物供体。Ammonium tetrathiomolybdate(VI) 具有神经保护作用。Ammonium tetrathiomolybdate(VI) 可用于脑缺血的研究。

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Ammonium tetrathiomolybdate(VI)的二维码
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  • 货号: ajcx12354
  • CAS: 15060-55-6
  • 别名:
  • 分子式: H8MoN2S4
  • 分子量: 260.27
  • 纯度: >98%
  • 溶解度: DMSO : 5 mg/mL (19.21 mM; Need ultrasonic)
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

Ammonium tetrathiomolybdate(VI) is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate(VI) has neuroprotection effects. Ammonium tetrathiomolybdate(VI) can be used for the research of brain ischemia[1].


Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10 mg/kg) confers significant neuroprotection[1].

Animal Model: Wistar Rats[1]
Dosage: 10 mg/kg
Administration: Intravenous
Result: Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size.


[1]. Bruna Pescador Mendon?a, et al. Neuroprotective effects of ammonium tetrathiomolybdate, a slow-release sulfide donor, in a rodent model of regional stroke. Intensive Care Med Exp. 2020 Apr 9;8(1):13.

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