Ammonium tetrathiomolybdate(VI) 是一种铜螯合剂,也是一类硫化物供体。Ammonium tetrathiomolybdate(VI) 具有神经保护作用。Ammonium tetrathiomolybdate(VI) 可用于脑缺血的研究。
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Ammonium tetrathiomolybdate(VI) is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate(VI) has neuroprotection effects. Ammonium tetrathiomolybdate(VI) can be used for the research of brain ischemia[1].
Ammonium tetrathiomolybdate(VI) (ATTM) (i.v.; 10 mg/kg) confers significant neuroprotection[1].
Animal Model: | Wistar Rats[1] |
Dosage: | 10 mg/kg |
Administration: | Intravenous |
Result: | Showed improved functional activity at both 24 h and 7-days post-reperfusion, in parallel with a significant reduction in infarct size. |
[1]. Bruna Pescador Mendon?a, et al. Neuroprotective effects of ammonium tetrathiomolybdate, a slow-release sulfide donor, in a rodent model of regional stroke. Intensive Care Med Exp. 2020 Apr 9;8(1):13.
DMNPE-caged ATP diammonium salt
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