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  • Burixafor hydrobromide (TG-0054 hydrobromide)
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Burixafor hydrobromide (TG-0054 hydrobromide)

Burixafor hydrobromide (TG-0054 hydrobromide) (TG-0054 hydrobromide) 是一种口服有效且有效的 CXCR4 拮抗剂,是一种良好的抗血管生成药物,在治疗脉络膜新生血管中具有潜在价值。

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Burixafor hydrobromide (TG-0054 hydrobromide)的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 5mg
    ¥1300.00
    1040.00
    - +
  • 50mg
    ¥5937.00
    4750.00
    - +
  • 100mg
    ¥9175.00
    7340.00
    - +
  • 200mg
    ¥14962.00
    11970.00
    - +
  • 500mg
    ¥30987.00
    24790.00
    - +
已选 0 0
金额: ¥0.00
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  • 货号: ajcx12426
  • CAS: 1191450-19-7
  • 别名: TG-0054 hydrobromide
  • 分子式: C27H51N8O3P.xHBr
  • 分子量:
  • 纯度: >98%
  • 溶解度: Water : 50 mg/mL
  • 储存: Store at -20°C
  • 库存: 现货

Background

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].



[1]. Shelke NB, et al. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res. 2011 Feb;1(1):76-90. [2]. Hsu WT, et al. CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction. Cell Transplant. 2015;24(7):1313-28.

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