6-Hydroxyflavone

6-Hydroxyflavone 是一种天然存在的黄酮化合物，具有抗炎作用。6-Hydroxyflavone 对牛血红蛋白 (BHb) 糖基化具有抑制作用。6-Hydroxyflavone 能激活 AKT、ERK 1/2、JNK 信号通路，有效促进成骨细胞分化。6-Hydroxyflavone 能抑制 LPS 诱导的 NO 的产生。

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100mg

￥550.00

440.00

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200mg

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500mg

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Background

6-Hydroxyflavone is a naturally occurring flavone, with anti-inflammatory activity. 6-Hydroxyflavone exhibits inhibitory effect towards bovine hemoglobin (BHb) glycation. 6-Hydroxyflavone can activate AKT, ERK 1/2, and JNK signaling pathways to effectively promote osteoblastic differentiation. 6-Hydroxyflavone inhibits the LPS-induced NO production[1] [2].

[1]. Das S, et al. Characterization of non-covalent binding of 6-hydroxyflavone and 5,7-dihydroxyflavone with bovine hemoglobin: Multi-spectroscopic and molecular docking analyses. J Photochem Photobiol B. 2018 Jan;178:40-52. [2]. Lai CH, et al. Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells. Evid Based Complement Alternat Med. 2014;2014:924560. [3]. Wang X, et al. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. PLoS One. 2015 Mar 19;10(3):e0116409.