17-trifluoromethylphenyl trinor Prostaglandin F2α isopropyl ester

Lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α

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库存: 现货

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1mg

￥937.00

750.00

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5mg

￥4162.00

3330.00

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10mg

￥7387.00

5910.00

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货号: ajcx17818
CAS: N/A
别名: 17trifluoromethylphenyl trinor PGF2α isopropyl ester
分子式: C27H37F3O5
分子量: 498.6
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 50 mg/ml,Ethanol:PBS(pH 7.2) (1:5): 0.2 mg/ml
储存: Store at -20°C
库存: 现货

Background

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.