GRP (porcine) (trifluoroacetate salt)

A neuropeptide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
500ug

￥2587.00

2070.00

- +
1mg

￥4100.00

3280.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajcx18514
CAS: N/A
别名: Porcine Gastrin-releasing Peptide 27
分子式: C126H198N38O31S2?XCF3COOH
分子量: 2805.3
纯度: >98%
溶解度: Water: 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to GRP receptors on St42 human gastric cancer cells with an IC50 value of 0.35 nM. GRP increases contractility of possum (T. vulpecula) gallbladder strips with an EC50 value of 1.34 nM. In vivo, GRP increases gastrin (ED50s = 0.70 and 0.47 nmol/kg2 per hour for peak and integrated values, respectively) and pancreatic polypeptide release (ED50s = 1.2 and 1.01 nmol/kg2 per hour for peak and integrated values, respectively) in conscious cats. It also increases acid and pepsin secretion (ED50s = 1.01 and 2.06 nmol/kg2 per hour, respectively) and increases antral stomach motility in conscious cats. GRP (28 μg/kg) reduces independent ad libitum intake of sucrose and milk from bottles by rats but does not affect intraoral intake of either solution from catheters.