ACTH (1-16) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

ACTH的肽段。

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库存: 现货

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数量
500ug

￥1050.00

840.00

- +
1mg

￥1950.00

1560.00

- +

已选 0 种 0 瓶

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货号: ajcx19288
CAS: N/A
别名: Adrenocorticotropic Hormone (1-16), SYSMEHFRWGKPVGKK-OH
分子式: C89H133N25O22S ? XCF3COOH
分子量: 1937.2
纯度: >98%
溶解度: Water: 1 mg/ml
储存: Store at -20°C
库存: 现货

Background

ACTH (1-16) is a peptide fragment of adrenocorticotropic hormone , a peptide hormone found in the brain that is involved in the biological stress response.¹ It binds to melanocortin receptors (MCRs; K_is = 0.267, 19, 698, and 2,600 nM for MC1R, MC3R, MC4R, and MC5R, respectively).² ACTH (1-16) (160 μg/kg, i.v.) increases mean arterial blood pressure (MAP) following bleeding-induced potension in a rat model of hemorrhagic shock 15-30 minutes after administration.³ It increases grooming behavior and the incidence of stretching and yawning syndrome (SYS) in rats when administered intraventricularly at 0.05 or 2 μg.⁴