A phytotoxic fungal metabolite
Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola.1 It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50 = 89 μM).2 Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50 = 38.4 μM).3,2
1.Stierle, A., Upadhyay, R.S., and Strobel, G.Cyperine, a phytotoxin produced by Ascochyta cypericola, a fungal pathogen of Cyperus rotundusPhytochemistry30(7)2191-2192(1991) 2.Dayan, F.E., Ferreira, D., Wang, Y.-H., et al.A pathogenic fungi diphenyl ether phytotoxin targets plant enoyl (acyl carrier protein) reductasePlant Physiol.174(3)1062-1071(2008) 3.Venkatasubbaiah, P., Van Dyke, C.G., and Chilton, W.S.Phytotoxic metabolites of Phoma sorghina, a new foliar pathogen of pokeweedMycologia84(5)715-723(1992)
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