ent-8-iso Prostaglandin F2α-d9

A neuropeptide with diverse biological activities

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库存: 现货

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10ug

￥2662.00

2130.00

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25ug

￥6287.00

5030.00

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50ug

￥11937.00

9550.00

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100ug

￥20975.00

16780.00

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货号: ajcx22416
CAS: N/A
别名: ent-8-epi PGF2αd9, ent-8-iso PGF2αd9, ent-15-F2t-Isoprostane-d9
分子式: C20H25D9O5
分子量: 363.5
纯度: >98%
溶解度: DMF: >100 mg/ml,DMSO: >100 mg/ml,Ethanol: >100 mg/ml,PBS (pH 7.2): 3 mg/ml
储存: Store at -20°C
库存: 现货

Background

ent-8-iso-Prostaglandin F_2α-d₉ (ent-8-iso-PGF_2α-d₉) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19',20,20, and positions. It is intended for use as an internal standard for the quantification of ent-8-iso-PGF_2α by GC- or LC-mass spectrometry. Isoprostanes are produced by the non-enzymatic, free-radical peroxidation of arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have a potent biological activity. ent-8-iso Prostaglandin F_2α (ent-8-iso PGF_2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC₅₀ values of 31 and 54 nM, respectively.¹

1.Hou, X., Robers, L.J., II, Gobeil, F., Jr., et al.Isomer-specific contractile effects of a series of synthetic F2-isoprostanes on retinal and cerebral microvasculatureFree Radical Biology & Medicine36(2)163-172(2004)