Picaridin-d3

An internal standard for the quantification of picaridin

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1mg

￥4612.00

3690.00

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货号: ajcx25480
CAS: N/A
别名: Icaridin-d3
分子式: C12H20D3NO3
分子量: 232.3
纯度: >98%
溶解度: Chloroform: slightly soluble,Methanol: slightly soluble
储存: -20°C
库存: 现货

Background

Picaridin-d₃ is intended for use as an internal standard for the quantification of picaridin by GC- or LC-MS. Picaridin is an insect repellant.^1,2,3 It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC₅₀s = 1,452 and 1,911 µM, respectively).¹ Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay.² It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m² on nets surrounding guinea pig cages.³ Formulations containing picaridin have been used as insect repellants against flies, mosquitoes, chiggers, ticks, and fleas.

1.Bohbot, J.D., and Dickens, J.C.Insect repellents: Modulators of mosquito odorant receptor activityPLoS One5(8)1-11(2010) 2.Syed, Z., Pelletier, J., Flounders, E., et al.Generic insect repellent detector from the fruit fly Drosophila melanogasterPLoS One6(3)e17705(2011) 3.Pennetier, C., Corbel, V., Boko, P., et al.Synergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiaeMalar. J.638(2007)