An ionizable cationic amino lipid
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CIN-16645 is an ionizable amino lipid.1 It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) to deliver single-guide RNA (sgRNA) targeting MHC class II transactivator (CIITA) in T cells.
1.Sridhar, S., Zhang, Y., Harrington, W.F., et al.Compositions and methods for reducing MHC class II in a cell(2022)
DMNPE-caged ATP diammonium salt
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