现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • CRT0066101 (hydrochloride)
CRT0066101 (hydrochloride)的可视化放大

CRT0066101 (hydrochloride)

Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling.

原价
¥562-3087
价格
450-2470
CRT0066101 (hydrochloride)的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci70894
  • CAS: 1290629-45-6
  • 别名:
  • 分子式: C18H22N6O?3HCl
  • 分子量: 447.8
  • 纯度: >98%
  • 溶解度: DMF: 0.1 mg/ml,DMSO: 3 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Water: 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2, and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, PKBα, MEK, ERK, c-Raf, c-Src, and c-Abl. It can block cell proliferation, induce apoptosis, and reduce the viability of pancreatic cancer cells both in vitro and in vivo.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服