A peptide substrate for AMPK
AMARA peptide is a synthetic peptide substrate for AMP-activated protein kinase (AMPK).1 It contains a serine at position seven that is subject to phosphorylation by AMPK and has been used to monitor AMPK activity in vitro and in vivo.1,2
1.Dale, S., Wilson, W.A., Edelman, A.M., et al.Similar substrate recognition motifs for mammalian AMP-activated protein kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase IFEBS Lett.361(2-3)191-195(1995) 2.Rybakowska, I.M., Slominska, E.M., Romaszko, P., et al.AMP-regulated protein kinase activity in the hearts of mice treated with low- or high-fat diet measured using novel LC-MS methodMol. Cell. Biochem.404(1-2)5-10(2015)
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