- 客服:
- 电话: 13061953619
- 微信:
E3 Ligase Ligand-Linker Conjugates 21 (Cereblon Ligand-Linker Conjugates 3) 是一种合成的 E3 连接酶配体-接头偶联物,其中包含用于 PROTAC 技术的基于 Thalidomide 的 cereblon 配体和 3 单元 PEG 接头。
E3 Ligase Ligand-Linker Conjugates 21 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 Ligase Ligand-Linker Conjugates 21 is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. E3 Ligase Ligand-Linker Conjugates 21 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].
[1]. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1
动态评分
0.0