E3 Ligase Ligand-Linker Conjugates 20

E3 Ligase Ligand-Linker Conjugates 20 (Cereblon Ligand-Linker Conjugates 2) 是一种合成的 E3 连接酶配体-接头偶联物，包含基于沙利度胺的 cereblon 配体和接头，可用于 PROTAC 的合成。

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库存: 现货

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数量
100mg

￥3737.00

2990.00

- +
500mg

￥14287.00

11430.00

- +
1g

￥26487.00

21190.00

- +
2g

￥37075.00

29660.00

- +

已选 0 种 0 瓶

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货号: ajce51022
CAS: 1950635-15-0
别名: Cereblon Ligand-Linker Conjugates 2; E3 Ligase Ligand-Linker Conjugates 20
分子式: C23H30N4O6
分子量: 458.51
纯度: >98%
溶解度: Soluble in DMSO
储存: Store at -20°C
库存: 现货

Background

E3 Ligase Ligand-Linker Conjugates 20 is a degron-linker (refer to Compound DL7-TL). The PROTAC linker is bound lo at least one targeting ligand.

Degron-linker-targeting ligand, wherein the linker is covalently bound lo at least one degron and at least one targeting ligand, the degron is a compound capable of binding to an ubiquitin ligase such as an E3 ubiquitin ligase (e g, cereblon), and the targeting ligand is capable of binding to the targeted protein (s)[1].

[1]. James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.