Tenatoprazole sodium

A proton pump inhibitor

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库存: 现货

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1mg

￥3262.00

2610.00

- +
5mg

￥6475.00

5180.00

- +
10mg

￥11012.00

8810.00

- +
20mg

￥19237.00

15390.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

Tenatoprazole is a proton pump inhibitor, blocking hog gastric H⁺/K⁺-ATPase activity with an IC₅₀ value of 6.2 ?M.¹ It is orally bioavailable, blocking induced gastric acid secretion and ulcer formation in rats and humans.^1,2,3 Tenatoprazole has a prolonged plasma half-life resulting in persistent effectiveness after withdrawal.³

1.Uchiyama, K., Wakatsuki, D., Kakinoki, B., et al.Effects of TU-199, a novel H+, K(+)-ATPase inhibitor, on gastric acid secretion and gastroduodenal ulcers in ratsMethods Find. Exp. Clin. Pharmacol.21(2)115-122(1999) 2.Galmiche, J.P., Bruley Des Varannes, S., Ducrotté, P., et al.Tenatoprazole, a novel proton pump inhibitor with a prolonged plasma half-life: effects on intragastric pH and comparison with esomeprazole in healthy volunteers.Aliment Pharmacol. Ther.19(6)655-662(2004) 3.Hunt, R.H., Armstrong, D., James, C., et al.Effect on intragastric pH of a PPI with a prolonged plasma half-life: Comparison between tenatoprazole and esomeprazole on the duration of acid suppression in healthy male volunteersAm. J. Gastroenterol.100(9)1949-1956(2005)