Mal-amido-PEG6-acid 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
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Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
DMNPE-caged ATP diammonium salt
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