84-B10

84-B10 是一种 3-苯基戊二酸衍生物。84-B10 抑制 cisplatin 诱导的肾小管铁死亡。84-B10 减轻 cisplatin 诱导的线粒体损伤和氧化应激。84-B10 改善 cisplatin 诱导的急性肾损伤 (AKI)。

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
5mg

￥1300.00

1040.00

- +
10mg

￥2175.00

1740.00

- +
25mg

￥4200.00

3360.00

- +
50mg

￥6475.00

5180.00

- +
100mg

￥9712.00

7770.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajcf18868
CAS: 698346-43-9
别名:
分子式: C25H22F3NO5
分子量: 473.44
纯度: >98%
溶解度: DMSO : 100 mg/mL (211.22 mM; ultrasonic and warming and heat to 60°C)
储存: Store at -20°C
库存: 现货

Background

84-B10 is a 3-phenylglutaric acid derivative. 84-B10 inhibits cisplatin (Decreased the sCr and BUN levels of cisplatin-exposed mice.
Attenuated renal tubules morphological abnormalities in a dose-dependent manner.
Decreased NGAL and KIM-1 levels in a dose-dependent manner.
Decreased the transcription levels of Lcn2 (which encodes NGAL) and Havcr1.

[1]. Fan J, et, al. A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis. Free Radic Biol Med. 2023 Jan;194:84-98.