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  • Adenosine-5'-O-diphosphoribose phosphate (sodium salt)
Adenosine-5'-O-diphosphoribose phosphate (sodium salt)的可视化放大

Adenosine-5'-O-diphosphoribose phosphate (sodium salt)

一种HMG-CoA还原酶抑制剂

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Adenosine-5'-O-diphosphoribose phosphate (sodium salt)的二维码
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  • 3.2mg
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  • 货号: ajcf22888
  • CAS:
  • 别名: Adenosine 2'-monophospho-5'-diphosphoribose, ADP-ribose Phosphate, P-ADP-Rib
  • 分子式: C15H20N5O17P3 ? 4Na
  • 分子量: 727.2
  • 纯度: >98%
  • 溶解度: Water: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Adenosine-5’-O-diphosphoribose phosphate (ADP-ribose phosphate) is an inhibitor of HMG-CoA reductase and a derivative of the nucleotide sugar ADP-ribose that is phosphorylated at the 2’ position.1 It selectively inhibits rat liver microsomal HMG-CoA reductase in its non-allosteric form with apparent Ki values of 53 and 550 μM at high and low thiol concentrations, respectively, which are associated with its non-allosteric and allosteric forms.

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