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SNS-032 (BMS-387032)
A Cdk2, Cdk7, and Cdk9 inhibitor
LEE011 succinate
A selective cyclin D1/CDK4 and cyclin D3/CDK6 inhibitor
Indirubin-3'-oxime
Inhibitor of GSK3β and cyclin-dependent kinases
GV-58
GV-58 is a novel, selective N-type and P/Q-type Ca2+ channels agonist with IC50s of 7.21 μM and 8.81 μM, respectively.
Palbociclib (PD0332991) Isethionate
Palbociclib (PD 0332991) isethionate 是一种具有口服活性的选择性 CDK4 和 CDK6 抑制剂,IC50 值分别为 11 和 16 nM。 Palbociclib (PD0332991) Isethionate 具有有效的抗增殖活性,可诱导癌细胞的细胞周期停滞,可用于 HR 阳性和 HER2 阴性乳腺癌和肝细胞癌的研究。
CYC065
An inhibitor of Cdk2 and Cdk9
Roscovitine (Seliciclib,CYC202)
A potent inhibitor of cyclin-dependent kinase 2
NU2058
An inhibitor of Cdk1 and Cdk2
LEE011 hydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride)
ON123300
A multi-kinase inhibitor
LY2835219 free base
A dual inhibitor of Cdk4 and Cdk6
NSC 693868
A selective inhibitor of Cdk1 and Cdk5
BI-1347
BI-1347 is small molecule inhibitor of Cyclin-dependent kinase 8(CDK8) with IC50 of 1.1 nM.
BS-181
A selective Cdk7 inhibitor