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N-type calcium channel blocker-1
N-typecalciumchannelblocker-1是有口服活性的麻醉剂,可阻断N型钙离子通道(N-typecalciumchannels),在IMR32试验中IC50值为0.7μM。
Ned 19
Ned 19 是一种选择性膜透性非竞争性 NAADP 拮抗剂,抑制 NAADP 介导的 Ca2+ 信号传导,IC50 为 65 nM。 Ned 19 强烈抑制小鼠的肿瘤生长和血管形成以及肺转移。
Isradipine (Dynacirc)
An L-type calcium channel blocker
(R)-(+)-Bay K 8644
CaCCinh-A01
A non-selective inhibitor of CaCCs
(±)-Methoxyverapamil (hydrochloride)
An L-type channel blocker
ONO-RS-082
A PLA2 inhibitor
FPL 64176
An L-type Ca2+ channel agonist
Cyclopiazonic acid
A mycotoxin and SERCA inhibitor
Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)
Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
Taltirelin acetate
Taltirelin acetate (TA-0910 acetate) 是一种促甲状腺激素释放激素受体 (TRH-R) 超激动剂,IC50 值为 910 nM,刺激细胞溶质Ca2+ 浓度增加 (Ca2+ 释放) 的 EC50 值为 36 nM。
Nitrendipine
Quin-2AM (Quin-2 acetoxymethyl ester)
A cell-permeant precursor of quin-2
L-651,582
A non-selective calcium channel blocker
Cav 2.2 blocker 1
Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain with IC50 of 0.001 μM.